Translational Biostatistician

  • Achilles Therapeutics
  • Job type: Permanent
  • Closing by 31/10/2019
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About Achilles Therapeutics: 

Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first product for Non-Small Cell Lung Cancer expected to enter the clinic in 2H 2019. 

Role Summary: 

We are seeking an ambitious and skilled Translational Biostatistician to join our Translational Science team. This team is responsible for the development and delivery of analyses that turn exploratory hypotheses into actionable insights from our clinical trial data. 

This role within the Translational team at Achilles will be pivotal for delivering robust statistical analyses evaluating exploratory hypotheses in our Translational Science program. 

This is a unique opportunity to join a company in an exciting start-up phase that has the ability to transform the clinical management of cancer. 

Responsibilities:  

The successful candidate will 

  • Help organise, model and integrate biological datasets from a variety of biological data sources (e.g. NGS, proteomics and IHC) to evaluate existing hypothesis and help guide the future direction of the Translational Science programme 
  • Work within the multidisciplinary Translational Science team; reporting and communicating results from analyses across the team and to the wider company 

This position requires:  

  • Recent PhD (or MSc and applicable work experience) in Statistics, or a numerate degree with a high component of statistical training 
  • In depth knowledge of statistical concepts and theory 
  • Demonstratable experience in handling, modelling and drawing inferences from large volumes of heterogenous datasets 
  • Authorship on high-quality papers in peer-reviewed journals
  •  Demonstrated fluency in either R or Python
  • Knowledge of UNIX based operating systems and prior use of computing clusters  
  • Very strong communication skills in order to convey statistical analyses and concepts 
  • Exceptional time management agility to deliver concurrent projects 
  • A clear ability to develop robust statistical analyses to fixed timescales 

 The following skills/experiences are desirable: 

  • Knowledge of Bayesian methodology, parameterisation and model comparison 
  • Prior experience in working in a clinical trials environment  

This is a permanent position, based in Stevenage, with a competitive salary and benefits package. 

Please send your CV with a covering letter by clicking Apply. 

Apply now

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