Research Associate

  • Achilles Therapeutics
  • Job type: Permanent
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About Achilles Therapeutics:
Achilles Therapeutics is a company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. We use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient and develop personalised T cell therapies. Originating from pioneering research at UCL, CRUK and the Francis Crick Institute, we are using our ground-breaking immuno-oncology approach to rapidly advance therapies, with our first product for Non-Small Cell Lung Cancer expected to enter the clinic in 2H 2019.

Role Summary:
We are seeking a bright, enthusiastic and motivated Research Associate with experience in immunological laboratory techniques to join our growing Process Development (PD) team in Stevenage to support the development of the next generation of personalised cancer medicines. As a Research Associate at Achilles Therapeutics you will report directly to one of the Principal Scientists within the Process Development team and support the team’s efforts to further optimise and develop different immune assays. You will also work closely with other members of the team to process blood and tumour from patient samples and run downstream assays. This is a unique opportunity to join a company in an exciting start-up phase that has the ability to transform the clinical management of cancer.

Responsibilities:
• Carry out immunoassays, including ELISpot and flow cytometry
• Assay optimisation
• Blood and tumour sample processing
• Follow established SOPs
• Record sample and analysis data accurately

Essential experience:
• MSc degree in a biological science discipline
• At least 2 years hands-on laboratory experience
• Experience in working with human blood samples, including PBMC isolation using density centrifugation
• Hands-on experience in a variety of immunoassays, including multicolour flow cytometry
• Excellent planning, organisational and time management skills, attention to detail
• Experience of independently designing, planning and executing experiments and interpreting data
• Self-motivated with strong initiative and drive and ability to work as part of a team
• Good communication and interpersonal skills
• Proficiency with MS Office

Desirable experience:
• Knowledge of immunology and cancer biology
• Experience in working with primary tumour tissue
• Hands-on experience in ELISpot assays
• Knowledge/experience of working in a GxP/GCLP environment
• Assay optimisation
• Peptide stimulation assays
• Knowledge/experience of peptide synthesis (LC-MS)

This is a permanent position, based in Stevenage, with a competitive salary and benefits package.

Please send your CV with a covering letter by clicking Apply.

Apply now

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