Careers

Reviral

ReViral are currently recruiting for a Virologist to join our laboratory team based at the SBC inStevenage, UK.

 We are recruiting for a practical laboratory-based position and are looking for an experienced graduate level scientist.  The role requires strong communication skills and an attitude of open and active collaboration. This exciting role will support ReViral’s discovery team providing key data for research programmes. An enthusiastic commitment to experimental work is essential for this position. 

Applicants should have:

•            A biological science degree

•            Proven experience of in vitro mammalian cell culture

•            Experience with virus culture is an advantage

•            Experience with small molecule compound management and databases such as Dotmatics is an advantage

•            Excellent interpersonal, oral and written communication skills

•            Ability to demonstrate eligibility to work in the United Kingdom

Applications (CV and cover letter) outlining qualifications and demonstrating how your experience and skills match the job requirements should be submitted by 6th March 2019 to info@reviral.co.uk.

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Autifony Therapeutics


Senior Molecular Biologist position 


BACKGROUND

Capitalising on basic science identified at GlaxoSmithKline, Autifony was spun out as a separate company in 2011. The company, which focuses on voltage-gated ion channel drugs for the treatment of serious disorders of the nervous system, has so far delivered two candidate molecules into Clinical development for hearing disorders and schizophrenia. Autifony operates a semi-virtual approach with a total staff number less than 20 and is based at the Stevenage Bioscience Catalyst in the UK and at Istituto di Ricerca Pediatrica Citta’ della Speranza in Padova Italy (www.autifony.com).
Requirements Autifony (Italy) is seeking a highly motivated self-starter with strong bench skills and who can work independently, to become part of a dynamic preclinical R&D group focused on developing new and effective therapeutics for Neurodegenerative diseases within the Neuroscience Therapeutic Area.
 
The successful applicant will participate in ongoing efforts directed toward developing new and effective therapeutics for Alzheimer’s disease.
 
This Senior Molecular Biologist position will be based at the Autifony laboratory at Istituto di Ricerca Pediatrica Citta’ della Speranza in Padova Italy.  


Responsibilities  |
• Planning, designing, completing and troubleshooting experiments 
• Analysis and interpretation of data, defining realistic timelines for studies and meeting delivery deadlines • Supervision of students 
• The candidate will be expected to prepare experimental summaries, protocols, presentations at internal and national meetings, and research papers for publication,
 
Desired Skills 
• Cell culture, including primary cells  
• Biochemistry and molecular biology experience e.g. Transient transfection,  DNA plasmid cloning and PCR, Western blotting and Immuno-precipitation 
• Immunofluorescence, Immunohistochemistry, Immuno-enzymatic assay (ELISA) 
• Confocal microscopy 
• Ability to work within a team 
• Applicants must have a good written and oral communication skills in English.
 
Experience 
• A strong research background in molecular biology, neuroscience, neural circuits underlying neurodegeneration pathways and pharmacology
 • Experience of working on the regulation on intracellular signalling pathways and biology related to some or all of the following: Autophagy, mitochondrial function and mitophagy, astrocyte activation and role in disease 

Qualifications • PhD in biological sciences
 
Autifony offers competitive salary packages, including performance related bonus and share option scheme.
 
APPLICATION PROCESS: For full consideration, please send a cover letter containing information regarding your research interests and plans and a CV, to: 
 
info@autifony.com and Nadia.pilati@autifony.com 

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Autifony Therapeutics


Junior Electrophysiologist Position


BACKGROUND

Capitalising on basic science identified at GlaxoSmithKline, Autifony was spun out as a separate company in 2011. The company, which focuses on voltage-gated ion channel drugs for the treatment of serious disorders of the nervous system, has so far delivered two candidate molecules into Clinical development for hearing disorders and schizophrenia. Autifony operates a semi-virtual approach with a total staff number less than 20 and is based at the Stevenage Bioscience Catalyst in the UK and at Istituto di Ricerca Pediatrica Citta’ della Speranza in Padova Italy (www.autifony.com).
 
Requirements Autifony (Italy) is seeking a highly motivated self-starter with strong bench skills and who can work independently, to become part of a dynamic preclinical R&D group focused on developing new and effective therapeutics for Neurodegenerative diseases within the Neuroscience Therapeutic Area.
 
This in vitro Junior Electrophysiologist position will be based at the Autifony laboratory at Istituto di Ricerca Pediatrica Citta’ della Speranza in Padova Italy
 
Responsibilities  • Planning, designing, completing and troubleshooting experiments • Data analysis and protocol design • The candidate will be expected to prepare experimental summaries, presentations at internal and national meetings, and research papers for publication,
 
Essential Skills
• Applicants must have  good written and oral communication skills in English.
• Ability to work independently • Highly motivated to learn new techniques
 
Experience
• The applicant should have a demonstrable track record  in vitro patch-clamp recordings (tissue slices and/or recombinant systems), neuroscience drug discovery, neural circuits underlying neurodegeneration pathways and pharmacology.
• Candidates with experience in screening and using automated patch clamp platforms are encouraged to apply.
 
Qualifications • PhD or MD degree in biological sciences
 
Autifony offers competitive salary packages, including performance related bonus and share option scheme.
 
APPLICATION PROCESS: For full consideration, please send a cover letter containing information regarding your research interests and plans and a CV, to: 
 
info@autifony.com and Nadia.pilati@autifony.com ------------------------------------------------------------------------------------------------------------------

Autifony Therapeutics


BACKGROUND

Capitalizing on basic science identified at GlaxoSmithKline, Autifony was spun out as a separate company in 2011. The company, which focuses on voltage-gated ion channel drugs for the treatment of serious disorders of the nervous system, has so far delivered two candidate molecules into Clinical development for hearing disorders and schizophrenia. Autifony operates a semi-virtual approach with a total staff number less than 20 and is based at the Stevenage Bioscience Catalyst in the UK (www.autifony.com).

Autifony is looking to expand its medicinal chemistry team, and is seeking a self-motivated, creative, and enthusiastic individual to become part of a dynamic preclinical R&D group.  The full-time junior chemist role will be based at the Autifony laboratory at the Stevenage Bioscience Catalyst in Hertfordshire, UK.

JUNIOR ROLE

A recent graduate with ideally 1-2 years of synthetic chemistry experience.  The successful candidate will be expected to design, synthesize and characterize new chemical entities under the direction of the head of lab

Essential Skills

·       Familiarity with the principles of synthetic and medicinal chemistry,

·      Creative thinking and ability to troubleshoot problems

·      Ability to plan and execute multiple synthetic transformations independently and apply appropriate analytical and purification techniques (NMR, Mass Spec, automated chromatography (Biotage), HPLC and LC-MS) to deliver fully characterized and pure target molecules from the milligram to gram quantities.

·      Experience in performing literature searches using chemistry databases(SciFinder) and in applying the results to solve synthetic challenges

·      Well organized and able to keep good records and documentation

·      Ability to work within a team

 

Experience

·       May have 1-2 years of chemistry laboratory experience in a Pharmaceutical, Biotech, or University environment

·      Working knowledge of the application of synthetic organic chemistry

·      Good manual and technical laboratory skills relevant to a chemistry laboratory

·       Familiar with good safe working practices and COSHH guidelines

 

Qualifications:

·      Degree or higher education qualification in a relevant chemistry discipline

 

Autifony offers competitive salary packages, including performance related bonus and share option scheme.

To apply please send your CV and a covering letter to the HR manager wendy.kennedy@autifony.com

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Freeline

We are based in Stevenage at the Stevenage Bioscience Catalyst, London at the Royal Free NHS Foundation Trust and Munich and are looking to expand our team.

We provide extraordinary career opportunities for talented individuals, who will have the opportunity to work with highly experienced leaders in science and business with proven track records in building successful businesses. Our success depends on the quality, experience and ambition of the individuals that join our team.

http://www.freelinetx.com/careers/








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